Quality & testing
How a lot earns its certificate
Four gates stand between a research-grade starting material and your bench. Skip any one of them and a lot doesn’t ship. Here’s the whole pipeline — and the 186 published reports it has produced so far.
STEP 01
Sourcing
Research-grade starting materials come from suppliers with audited quality systems. Every inbound lot is quarantined and identity-checked before synthesis begins — wrong-compound and low-purity inputs are the peptide market's most common defect, so this gate comes first.
STEP 02
GMP synthesis & lyophilization
Peptides are synthesized, purified, and lyophilized into sealed vials at a GMP-registered facility, with documented batch records, equipment cleaning logs, and in-process checks at every stage.
STEP 03
Third-party testing
Finished lots go to an independent third-party analytical laboratory for identity by ESI mass spectrometry, purity by RP-HPLC, net peptide content, and bacterial endotoxin testing. Additional panels — water content, counterion, bioburden — are run where they matter.
STEP 04
Published per-lot COAs
The laboratory's Certificate of Analysis is published to our public library before the lot is released for sale. The lot number on your vial is the key to the exact report for the material in your hand — not a marketing sample.
The bar
Specifications every lot must clear
Release specifications follow established analytical methods for research peptides — identity, purity, net content, and safety attributes verified on every lot.
| Test | Method | Specification |
|---|---|---|
| Identity | ESI mass spectrometry (ESI-MS) | Found mass matches theoretical |
| Purity | Reverse-phase HPLC (RP-HPLC) | ≥ 98% |
| Net peptide content | Nitrogen analysis / amino acid analysis | ≥ 80% |
| Single impurity (max) | RP-HPLC, area % | ≤ 1.0% |
| Water content | Karl Fischer titration | ≤ 8.0% |
| Acetate / counterion | Ion chromatography | ≤ 15% |
| Heavy metals | ICP mass spectrometry (ICP-MS) | ≤ 10 ppm |
| Bacterial endotoxin | LAL (kinetic chromogenic) | ≤ 10 EU/mg |
| Bioburden | Total viable count | < 10 CFU/vial |
Methods and limits shown are placeholder specifications for demonstration — verify against your actual analytical program and each lot’s COA before launch.
Inside the lab
Where the numbers come from
Every lot is released by Aegis Bioanalytical Laboratories, an independent ISO/IEC 17025-accredited laboratory in San Diego, CA.
Every lot is released by Aegis Bioanalytical Laboratories, an independent ISO/IEC 17025-accredited laboratory — HPLC purity, mass-spec identity, and heavy-metal screening on file for each batch.
Don’t take this page’s word for it
The proof isn’t the process story — it’s the paperwork. Every certificate is in the library.